9, 10Īn adequate level of vitamin B12 is important for maintaining nerve health. In general, sitting for long periods of time without proper posture, frequently bending the spine forward or sideways, and/or regularly lifting the arms above shoulder level are risk factors for sciatica. A few examples include truck drivers, machine workers, carpenters, and weight-lifting athletes. People with certain occupations may be at a higher risk of developing sciatica pain. Men, however, are reported to have more hospitalizations and surgery due to sciatica Occupational causes Research also shows that sciatica tends to occur more often in women, who may experience slower recovery in severe cases. Older individuals who are tall (typically over 180 cm for men and 170 cm for women) 7.Research indicates a higher risk of sciatica may be present in: 4 Physical characteristicsĬertain physical characteristics of an individual may affect the sciatic nerve, causing sciatica. It is believed that these substances are released due to the reaction between nerve roots and exposed disc material and may cause inflammation of the sciatic nerve. Certain substances such as glycosphingolipids (fats) and neurofilaments (protein polymers) that are secreted by the immune system are particularly high in people with sciatica. Some studies suggest that immune system responses may play a role in causing sciatica pain when there is exposure of disc material from herniated discs. 2 - 4 Sometimes, degenerated discs may cause nerve tissues to grow into the disc, penetrating the outer and inner layers of the disc, causing sciatica pain. These chemical irritants are thought to include substances like hyaluronic acid and/or fibronectin (protein) fragments that leak out of degenerated or herniated discs.
Research indicates that chemical irritants may cause inflammation and/or irritation of the sciatic nerve. Reference: Sciatica Overview Chemical inflammation Rarely, tumors, cysts, infection, or abscesses in the lower spine or pelvic region may compress the sciatic nerve Instability of a vertebral segment that occurs if one vertebra slips over the one below it (spondylolisthesis), vertebral defects ( spondylolysis ), or complete dislocation of one or more vertebrae may directly compress the nerve root(s) of the sciatic nerve. Other degenerative changes in the spine, such as thickening of facet joint capsules and/or ligaments, may also directly compress the sciatic nerve. Stenosis, or narrowing of the intervertebral opening through which the sciatic nerve roots travel, may compress or irritate the sciatic nerve. A disc in the lower back may bulge or herniate, causing irritation, and/or compression of a sciatic nerve root. Watch: Sciatic Nerve Anatomy Video Mechanical compressionĭirect physical forces may be applied to the nerve due to the following common conditions:
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